| J | Date | Locaux | Score | Visiteurs | MT | Spect | >2.5 | MT | Re | Note | Arb. | |
| 22 | 02/02/2008 | Betis Sevilla | 0 - 1 | Deportivo | 0-1 | 35 000 | Non | 2 | 2 | 0 | 0 | |
| 22 | 02/02/2008 | UD Almería | 2 - 0 | Real Madrid | 1-0 | 15 000 | Non | 1 | 1 | 0 | 0 | |
| 22 | 03/02/2008 | Atlético Madrid | 1 - 1 | Real Murcia | 0-0 | 35 000 | Non | N | N | 0 | 0 | |
| 22 | 03/02/2008 | Barcelona | 1 - 0 | Osasuna | 0-0 | 56 221 | Non | N | 1 | 0 | 0 | |
| 22 | 03/02/2008 | Getafe CF | 0 - 1 | Espanyol | 0-1 | 6 000 | Non | 2 | 2 | 0 | 0 | |
| 22 | 03/02/2008 | Levante UD | 1 - 1 | Racing | 0-0 | 10 548 | Non | N | N | 0 | 0 | |
| 22 | 03/02/2008 | Real Valladolid | 0 - 2 | Valencia CF | 0-0 | 16 300 | Non | N | 2 | 0 | 0 | |
| 22 | 03/02/2008 | Real Zaragoza | 1 - 0 | Athletic Bilbao | 1-0 | 28 000 | Non | 1 | 1 | 0 | 0 | |
| 22 | 03/02/2008 | Recreativo | 1 - 2 | FC Sevilla | 0-1 | 20 000 | Oui | 2 | 2 | 0 | 0 | |
| 22 | 03/02/2008 | Villarreal CF | 1 - 1 | Real Mallorca | 1-1 | 18 000 | Non | N | N | 0 | 0 |
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